Study of Adalimumab in Subjects With Moderate to Severe Chronic Hidradenitis Suppurativa

Completed · Phase 2 · Has a placebo group

Conditions studied: Hidradenitis Suppurativa

In brief

This study will investigate how well adalimumab works in people with hidradenitis suppurativa (HS) in the short and long term.

Key facts

Study ID

NCT00918255

Run by

Abbott

People needed

154

Starts

2009-04-01

Expected to finish

2010-11-01

Last updated by the study team

2011-05-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults with stable, moderate to severe hidradenitis suppurativa
• Negative Chest X-ray and PPD test at Screening. If participant has had a past ulcerative reaction to PPD placement and/or chest X-ray consistent with prior tuberculosis exposure, the participant must initiate, or have documented completion of, a course of anti-tuberculosis therapy.
• Ability to administer subcutaneous injections
• General good health otherwise

You may not qualify if…

• Prior anti-TNF therapy
• Unstable antibiotic therapy for HS
• Required medication washouts for other HS treatments
• Prior exposure to Tysabri® (natalizumab);
• Recent infection requiring treatment
• Significant medical events or conditions that may put patients at risk for participation
• Female subjects who are pregnant or breast-feeding or considering becoming pregnant during the study;
• History of cancer, except successfully treated skin cancer
• Recent history of drug or alcohol abuse

Where it is running

• Site Ref # / Investigator 19062 — Birmingham, Alabama, United States
• Site Ref # / Investigator 18201 — Bakerfield, California, United States
• Site Ref # / Investigator 18467 — Los Angeles, California, United States
• Site Ref # / Investigator 18207 — San Diego, California, United States
• Site Ref # / Investigator 18204 — Miami, Florida, United States
• Site Ref # / Investigator 18209 — Atlanta, Georgia, United States
• Site Ref # / Investigator 18202 — Skokie, Illinois, United States
• Site Ref # / Investigator 18211 — Evansville, Indiana, United States
• Site Ref # / Investigator 18203 — Boston, Massachusetts, United States
• Site Ref # / Investigator 18210 — Boston, Massachusetts, United States
• Site Ref # / Investigator 18461 — St Louis, Missouri, United States
• Site Ref # / Investigator 18466 — Omaha, Nebraska, United States
• Site Ref # / Investigator 19141 — New York, New York, United States
• Site Ref # / Investigator 18208 — New York, New York, United States
• Site Ref # / Investigator 19001 — Winston-Salem, North Carolina, United States
• Site Ref # / Investigator 18981 — Hershey, Pennsylvania, United States
• Site Ref # / Investigator 18464 — Philadelphia, Pennsylvania, United States
• Site Ref # / Investigator 19061 — Dallas, Texas, United States
• Site Ref # / Investigator 18463 — San Antonio, Texas, United States
• Site Ref # / Investigator 18206 — Norfolk, Virginia, United States
• Site Ref # / Investigator 18683 — Copenhagen NV, Denmark
• Site Ref # / Investigator 18684 — Roskilde, Denmark
• Site Ref # / Investigator 18471 — Dessau, Germany
• Site Ref # / Investigator 18469 — Kiel, Germany
• Site Ref # / Investigator 18470 — Amsterdam, Netherlands

Full record on ClinicalTrials.gov

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