Evaluation of High-Density Lipoprotein in Obesity Study

Stopped early

Conditions studied: Obesity

In brief

Obesity is associated with an impaired functioning HDL (good cholesterol) resulting in an acceleration in the development of atherosclerosis. This study will evaluate HDL functionality in patients with BMI (Body Mass Index) 20 - 25 and BMI \>30

Key facts

Study ID

NCT00912236

Run by

The Cleveland Clinic

People needed

77

Starts

2009-06-01

Expected to finish

2012-03-01

Last updated by the study team

2017-04-13

Who can join

Age: 20 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Group 1:
• Age 20-80
• English speaking
• BMI 20-25 kg/m2
• Group 2:
• Age 20-80
• English speaking
• BMI > 30 kg/m2
• TG > 150 and
• HDL > 50 (females) >40 (Males)
• Group 3:
• Age 20-80
• English speaking
• BMI > 30 kg/m2
• TG > 150 and
• HDL < 50 (females) < 40 (males)

You may not qualify if…

• Self-reported history of:
• Diabetes mellitus
• Any previous lipid therapy within the last three months
• Macrovascular events including TIA, stroke, myocardial infarction, heart failure, claudication, or known peripheral vascular disease
• Current pregnancy

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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