Feasibility Study of Exercise in Patients With Leg Blood Clots

Completed · Not applicable

Conditions studied: Deep Vein Thrombosis

In brief

The purpose of this pilot study is to assess the feasibility of determining the effects of a structured exercise program started two to four weeks after diagnosis of a first episode lower-extremity deep vein thrombosis (DVT) for a period of 12 weeks in reducing the incidence of post-thrombotic syndrome (PTS).

Key facts

Study ID

NCT00910364

Run by

University of Oklahoma

People needed

5

Starts

2008-10-01

Expected to finish

2016-12-01

Last updated by the study team

2017-04-13

Who can join

Age: 21 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• First episode lower extremity DVT (proximal or distal) documented by ultrasound, CT angiogram or venogram within last 4 weeks.
• Treatment with LMWH, or unfractionated heparin (UFH) followed by warfarin adjusted to keep INR 2 to 3 for at least 3 months, or LMWH given in therapeutic doses as sole therapy.
• Age 21 to 75 years old.

You may not qualify if…

• Recurrent DVT.
• Treatment of DVT with systemic or catheter-directed thrombolysis Contraindications to exercise training according to the American College of Sports Medicine (e.g., acute myocardial infarction, unstable angina, etc.,).
• Life expectancy < 1 year.
• Pregnancy.
• Geographic inaccessibility.
• Screening (pre-randomization) exercise stress test demonstrating contraindication to exercise training (see exclusion #2).
• Cognitive dysfunction assessed by mini-mental status exam (score < 24).
• Inability to walk.

Where it is running

• University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

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