Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index

Completed

Conditions studied: Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia

In brief

The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.

Key facts

Study ID

NCT00907439

Run by

Washington University School of Medicine

People needed

21

Starts

2008-11-01

Expected to finish

2010-10-01

Last updated by the study team

2010-11-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Non-emergent coronary bypass grafting surgery
• Left ventricular ejection fraction of 40% or greater

You may not qualify if…

• Myocardial infarction within 4 weeks
• Greater than mild cardiac valvular pathology
• Body mass index greater than 35
• Cardiac dysrhythmias or pacemaker therapy
• Left bundle branch block
• Uncontrolled gastroesophageal reflux disease

Where it is running

• Barnes-Jewish Hospital — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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