Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department
Withdrawn before enrolling
Conditions studied: Acute Myocardial Infarction, Chest Pain, Acute Coronary Syndrome
In brief
This is a multi-center study to assess the diagnostic accuracy of the Troponin I assay in the Biosite Triage Cardio3 Panel at the point-of-care (POC) in adults presenting to the emergency department with possible acute myocardial infarction (AMI).
Key facts
- Study ID
- NCT00907231
- Run by
- Abbott RDx Cardiometabolic
- People needed
- 0
- Starts
- 2010-02-01
- Expected to finish
- 2010-05-01
- Last updated by the study team
- 2015-07-21
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years of age or older at time of enrollment
- Presenting to the ED within 6 hours from onset of chest discomfort (pain, pressure, tightness, etc) consistent with a possible diagnosis of AMI or ACS and with an initial ECG non-diagnostic for injury (or injury equivalent resulting in emergent reperfusion therapy). (NOTE: Subjects who have chest discomfort that is episodic or stuttering in nature may be included if the ED presentation is within 6 hours of symptom onset.)
- Experiencing at least 30 minutes of chest pain or other anginal equivalent symptoms. (Note: Subjects who have symptoms of shorter duration due to pharmacologic intervention may be included.)
You may not qualify if…
- Patient (or Legal Representative) unable or unwilling to provide written informed consent.
- Patient unwilling or unlikely to comply with study procedures, including protocol-specified blood sampling or telephone follow-up at 30 days and 6 months.
- Vulnerable populations as deemed inappropriate for study by site principal investigator.
- ST-elevation or other ECG criteria that result that is diagnostic for AMI and results in patient being sent for percutaneous coronary interventions (PCI) or being treated with thrombolytics6.
- Pulmonary Edema requiring CPAP, BIPAP, or mechanical ventilation
- Tachyarrhythmias (SVT, V-Tach, rapid atrial fib)
- End Stage Renal Disease on Hemodialysis
- Cardiac Arrest prior to arrival
- Implantable Defibrillator firing prior to arrival
- Hemodynamically unstable patients
- Trauma injury to the chest
Where it is running
- Loyola University Medical Center — Maywood, Illinois, United States
- Stony Brook University Medical Center — Stony Brook, New York, United States
- Oregon Health and Sciences University — Portland, Oregon, United States
- Allegheny General Hospital — Pittsburgh, Pennsylvania, United States
- Erlanger Medical Center — Chattanooga, Tennessee, United States
- Mountain States Health Alliance — Johnson City, Tennessee, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.