CP-690,550 and Midazolam Drug-Drug Interaction Study

Completed · Phase 1

Conditions studied: Healthy Volunteer

In brief

CP-690,550 and midazolam are metabolized by similar enzymes in the liver. This study is designed to assess whether co-administration of CP-690,500 and midazolam will effect the metabolism of midazolam in healthy volunteers.

Key facts

Study ID

NCT00902460

Run by

Pfizer

People needed

25

Starts

2009-06-01

Expected to finish

2009-07-01

Last updated by the study team

2009-08-13

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy male and/or female (non-child bearing potential) subjects

You may not qualify if…

• Clinically significant infections within the past 3 months
• History of previously untreated infection with Mycobacterium tuberculosis
• Positive screening test for hepatitis B surface antigen, anti-hepatitis C antibody, or human immunodeficiency virus

Where it is running

• Pfizer Investigational Site — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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