Immune Responses Induced by Different Licensed Influenza Vaccines

Completed · Not applicable

Conditions studied: Immune Response

In brief

The goal of this research is to find out how the body's immune system responds to different manufacturer's "flu" vaccines.

Key facts

Study ID

NCT00902278

Run by

University of Massachusetts, Worcester

People needed

193

Starts

2008-10-01

Expected to finish

2016-04-01

Last updated by the study team

2017-11-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults (18-50 years of age)
• Willing to donate a blood sample multiple times
• Willing to sign informed consent and HIPAA

You may not qualify if…

• Known systemic hypersensitivity reactions to egg proteins (eggs or egg products), to chicken proteins
• Known hypersensitivity to neomycin, thimerosol (mercury derivative), neomycin, or polymyxin
• Previous life threatening reaction to influenza vaccine
• Individuals with altered immunocompetence state from medical condition ( HIV, cancer) or through immunosuppressive therapy(irradiation,corticosteroids, antimetabolites, alkylating agents, cytotoxic agents)
• Occurrence of neurological syndrome within six weeks of previous influenza immunization
• Active neurological disorder characterized by changing neurological disorder
• Pregnancy
• Acute febrile illness
• History of anemia or bleeding disorders

Where it is running

• University of Massachusetts Medical School — Worcester, Massachusetts, United States

Full record on ClinicalTrials.gov

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