Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload

Completed · Phase 2

Conditions studied: Thalassemia, Iron Overload

In brief

This is a pilot study looking at the safety and efficacy of giving combination chelation with deferasirox and deferoxamine. The hypothesis is that combination chelation is safe in decreasing overall iron in patients with thalassemia.

Key facts

Study ID

NCT00901199

Run by

Elliott Vichinsky

People needed

22

Starts

2007-09-01

Expected to finish

2012-10-01

Last updated by the study team

2021-08-12

Who can join

Age: 8 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Transfusion Dependent Thalassemia
• If iron between 5-15 mg/g dry liver by SQUID, subject must have a documented endocrinopathy or cardiac finding
• Older than 8 years

You may not qualify if…

• Participating on another interventional clinical trial

Where it is running

• CHRCO — Oakland, California, United States

Full record on ClinicalTrials.gov

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