Plant-based Dietary Intervention for Treatment of Acne

Completed · Not applicable

Conditions studied: Acne

In brief

The purpose of this study is to determine if a low-fat, vegan diet affects the number of acne lesions, acne severity, and acne extent.

Key facts

Study ID

NCT00900939

Run by

Physicians Committee for Responsible Medicine

People needed

43

Starts

2009-07-01

Expected to finish

2010-03-01

Last updated by the study team

2012-08-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or female gender
• Mild, moderate, or severe acne, as indicated by an Evaluator Global Severity Score (EGSS) score of 2, 3, or 4
• Presence of at least 10 inflammatory or 20 non-inflammatory lesions on the face
• Presence of acne for at least 3 months (by volunteer's history)
• Age at least 18 years
• Ability and willingness to participate in all components of the study
• Willingness to be assigned randomly to a low-fat, vegan diet or a control group
• Intention to remain in the Washington DC area for the 16-week study period.

You may not qualify if…

• Change in use or dosage of hormone-based contraceptives in the last 3 months or anticipated change during the study period.
• Use of depot medoxyprogesterone contraception
• Use of oral retinoids in the last 6 months
• Use of high doses of vitamin A in the last 3 weeks (≥ 10,000 IU)
• Use of oral antibiotics or topical antibacterial or retinoid agents in the last 1 month
• Presence of more than two nodules or cysts on the face or more than two nodules or cysts on the back and chest.
• Use of medications known to cause or exacerbate acne including lithium, oral or injected steroids, or medications containing iodides or bromides
• History of alcohol abuse or dependency followed by any current use
• Current or unresolved past drug or alcohol abuse
• Facial hair that would interfere with making acne assessments
• Pregnancy or breastfeeding (currently or in the past 3 months), or intent to become pregnant in the next 4 months
• History of severe mental illness within the past 3 years
• Unstable medical status
• Current dietary pattern that is low-fat and vegan
• Anticipated difficulty attending or participating in group sessions
• Inordinate fear of blood draws
• Diabetes treated with insulin or any other medications.

Where it is running

• Washington Center for Clinical Research — Washington D.C., District of Columbia, United States

Full record on ClinicalTrials.gov

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