Effects of Daytime Eszopiclone Administration in Shift Workers

Completed · Not applicable · Has a placebo group

Conditions studied: Shift-Work Sleep Disorder

In brief

The purpose of this study is to test the effects of eszopiclone on daytime sleep and overnight wakefulness in shift workers.

Key facts

Study ID

NCT00900159

Run by

Brigham and Women's Hospital

People needed

24

Starts

2009-05-01

Expected to finish

2010-02-01

Last updated by the study team

2017-08-30

Who can join

Age: 20 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 20-50 (men or women)
• Current shift worker (for at least 3 months, at least 5 overnights/month and 3 consecutive)
• A willingness and ability to comply with study procedures
• If of child-bearing potential, using a medically-accepted method of birth control, including abstinence, barrier method with spermicide, steroidal contraceptive (oral, transdermal, implanted, or injected) in conjunction with a barrier method, or intrauterine device [IUD]).

You may not qualify if…

• Current diagnosis of DSM-IV Axis I disorder (other than insomnia)
• Regular treatment (>1time/wk) with CNS-active medication within 1 month of first inpatient visit
• Uncontrolled medical illness that would interfere with participation in the study
• BMI>32 or < 19.8 kg/m2
• Current symptoms or diagnosis of any moderate to severe sleep disorder other than SWSD
• Periodic Leg Movement of Sleep Index (PLMSi)>20/hr of sleep or Respiratory Desaturation Index (RDI)>15 on polysomnography (PSG)
• Current alcohol or drug dependence/abuse
• Menopausal or peri-menopausal symptoms that disrupt sleep
• Pregnant, lactating, or planning to become pregnant
• Current smoking of more than 10 cigarettes per day
• Current use of over the counter sleep aids such as Benadryl or melatonin

Where it is running

• Brigham & Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.