Effect of Saturated Fat on Large Low-density Lipoprotein (LDL) and High-density Lipoprotein (HDL)

Completed · Not applicable

Conditions studied: Dyslipidemia

In brief

The purpose of the study is to test whether increased saturated fat intake results in increased levels of larger LDL and HDL particles in individuals with LDL Pattern B.

Key facts

Study ID

NCT00895141

Run by

UCSF Benioff Children's Hospital Oakland

People needed

53

Starts

2009-04-01

Expected to finish

2011-04-01

Last updated by the study team

2013-01-14

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men or postmenopausal woman between 18-70 yrs
• Body Mass Index between 25-35
• Blood pressure <150/90
• Non smoking
• Agrees to consume no alcohol or dietary supplements during the study
• LDL Subclass Pattern B
• Total cholesterol and LDLC ≤95th percentile for sex and age
• Fasting triglycerides ≤ 500mg/dl
• Fasting blood sugar < 126 mg/dl
• At least 3 months weight stable

You may not qualify if…

• History of coronary heart disease, cerebrovascular disease, peripheral vascular disease, bleeding disorder, liver or renal disease, diabetes, lung disease, HIV, or cancer (other than skin) in the last 5 years
• Taking drugs known to affect lipid metabolism or hormones
• Abnormal thyroid stimulating hormone (TSH)

Where it is running

• Cholesterol Research Center — Berkeley, California, United States

Full record on ClinicalTrials.gov

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