The Effect of Prescription Medications in Marijuana Users

Completed · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Marijuana Abuse

In brief

A subset of heavy marijuana users have trouble quitting marijuana use and the number of those seeking treatment for problems related to marijuana is increasing. The purpose of this research study is to investigate whether dronabinol can reduce withdrawal effects associated with stopping marijuana use, if dronabinol can reduce the rewarding effects of smoked marijuana, and whether there are any cognitive performance deficits associated with dronabinol doses that produce such effects.

Key facts

Study ID

NCT00893074

Run by

Johns Hopkins University

People needed

24

Starts

2009-04-01

Expected to finish

2011-10-01

Last updated by the study team

2017-08-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• current use of marijuana
• able to give informed consent

You may not qualify if…

• dependence on drug other than marijuana
• pregnant, breast feeding, or planning to become pregnant within the next 3 months
• currently seeking treatment for cannabis-related problems or otherwise trying to reduce use
• use of cannabis under the guidance of a physician for a medical disorder
• unstable or uncontrolled cardiovascular disease (e.g., hypertension, angina)
• allergy to study medication

Where it is running

• Behavioral Pharmacology Research Unit — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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