Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
Stopped early · Phase 1
Conditions studied: Lung Cancer, Metastatic Cancer
In brief
RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving everolimus together with whole-brain radiation therapy may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of everolimus and to see how well it works when given together with whole-brain radiation therapy in treating patients with brain metastasis from non-small cell lung cancer.
Key facts
- Study ID
- NCT00892801
- Run by
- Vanderbilt-Ingram Cancer Center
- People needed
- 5
- Starts
- 2009-05-01
- Expected to finish
- 2011-02-01
- Last updated by the study team
- 2012-03-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Vanderbilt-Ingram Cancer Center - Cool Springs — Nashville, Tennessee, United States
- Vanderbilt-Ingram Cancer Center — Nashville, Tennessee, United States
Full record on ClinicalTrials.gov
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