Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study)

Completed

Conditions studied: Anemia, Sickle Cell

In brief

Sickle cell anemia (SCA) is an inherited blood disorder that can cause organ damage. The BABY HUG study is evaluating the use of the medication hydroxyurea at preventing organ damage in children with SCA. The purpose of this follow-up study is to evaluate the long-term effects of hydroxyurea in children who have participated in the BABY HUG study.

Key facts

Study ID

NCT00890396

Run by

National Heart, Lung, and Blood Institute (NHLBI)

People needed

163

Starts

2008-09-01

Expected to finish

2011-12-01

Last updated by the study team

2020-08-20

Who can join

Age: 2 and older, up to 7. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All children who completed at least 18 months of follow-up visits in the initial BABY HUG study
• Children from the initial BABY HUG study who are on a chronic transfusion program or who are recipients of a bone marrow transplant

You may not qualify if…

• Any child who was not enrolled in the initial BABY HUG study for at least 18 months

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Howard University College of Medicine — Washington D.C., District of Columbia, United States
• University of Miami School of Medicine — Miami, Florida, United States
• Emory University School of Medicine — Atlanta, Georgia, United States
• Johns Hopkins University School of Medicine — Baltimore, Maryland, United States
• Children's Hospital of Michigan/Wayne State University — Detroit, Michigan, United States
• University of Mississippi Medical Center — Jackson, Mississippi, United States
• Downstate Medical Center — Brooklyn, New York, United States
• Duke University Medical Center — Durham, North Carolina, United States
• Drexel University — Philadelphia, Pennsylvania, United States
• Medical University of South Carolina — Charleston, South Carolina, United States
• St. Jude Children's Research Hospital — Memphis, Tennessee, United States
• University of Texas Southwestern Medical Center at Dallas — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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