Functional and Physiological Responses to Lokomat Therapy (Pilot Study)

Completed

Conditions studied: Spinal Cord Injuries, Multiple Sclerosis, Stroke

In brief

Individuals with neurological deficiencies such as those who have spinal cord injury, stroke, traumatic brain injury, Parkinson's disease, and multiple sclerosis often lose their ability to ambulate over ground. Loss of functional mobility not only impedes everyday life, but may also affect many systems and organs in the body. The investigators are interested in obtaining a wide variety of data in order to obtain a better understanding of changes that occur as a result of receiving Lokomat therapy. The investigators will be studying body composition, cardiac, pulmonary, endocrine, metabolic, and molecular changes after a 12-week clinical therapy program.

Key facts

Study ID

NCT00883142

Run by

US Department of Veterans Affairs

People needed

27

Starts

2006-10-01

Expected to finish

2013-03-01

Last updated by the study team

2013-06-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The inclusion criteria are based on the guidelines set by the clinical Lokomat therapy program.
• Patients will have been evaluated on the Rehabilitation Service for entry into the clinical therapy program.
• Any patient who is already eligible for Lokomat therapy is a candidate for this research project.

You may not qualify if…

• Pregnant women
• History of fractures of the lower extremities
• Bone density study indicating bone loss greater than 5 standard deviations from normal.
• Fixed contractures of the ankles, knees or hips
• Uncontrolled spasticity that significantly interferes with movement of lower extremities.
• Uncooperative, unmotivated patients or patients whom cannot follow instructions on a consistent basis or communicate effectively with the treating clinicians.
• Pressure ulcers over the greater trochanters, ischial tuberosities and sacrum.
• Weight greater than 250 lbs
• severe orthostatic hypotension (drop in blood pressure more than 30mm Hg when moving from sitting to standing posture)
• Acute medical illness (i.e. infection)
• Recently documented DVT in lower extremities
• SCI ASIA's A and B

Where it is running

• VA Medical Center, Bronx — The Bronx, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.