Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions

Recruiting now

Conditions studied: Tissue Adhesions

In brief

Official title: Sensitivity and predictive value of functional cine magnetic resonance imaging (MRI) detecting intra-abdominal adhesions Background: Adhesions are a frequent problem in abdominal surgery. The formation of adhesions is part of a normal wound healing. However in some patients adhesions cause severe complications such as chronic pain, obstruction and strangulation of the bowel. Adhesions can also obstruct access to the peritoneal cavity and complicate reoperations. Accurate imaging of adhesions would be of benefit avoiding adhesion related complications at repeated laparotomy or laparoscopy. At present no validated diagnostic tool mapping adhesions exists. Purpose: To define the sensitivity and specificity of functional cineMRI in detecting and mapping adhesions in patients undergoing reoperation. Design: Prospective multicenter observational trial Primary outcome: Sensitivity and specificity of functional MRI detecting adhesions to the abdominal wall Secondary outcome: Sensitivity and specificity of functional MRI detecting organ-to-organ adhesions. Estimated enrollment: 100 Estimated study completion date: dec 2019 Estimated primary completion date: dec 2019

Key facts

Study ID

NCT00882167

Run by

Radboud University Medical Center

People needed

100

Starts

2009-04-01

Expected to finish

2025-12-01

Last updated by the study team

2025-01-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with a median abdominal scar due to a previous open abdominal surgical procedures with a length of at least 10 cm and have given written consent.

You may not qualify if…

• Severe claustrophobia.
• No MRI allowed

Where it is running

• Radboud University Nijmegen Medical Center — Nijmegen, Gelderland, Netherlands (enrolling)
• Rijnstate Hospital — Arnhem, Gelderland, Netherlands
• Jeroen Bosch Hospital — 's-Hertogenbosch, Netherlands
• Gelre Hospital — Apeldoorn, Netherlands
• Catharina Hospital — Eindhoven, Netherlands

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.