Memantine in the Treatment of Kleptomania

Completed · Phase 2

Conditions studied: Kleptomania

In brief

The goal of the proposed study is to evaluate the efficacy and safety of memantine in kleptomania.

Key facts

Study ID

NCT00880685

Run by

University of Chicago

People needed

12

Starts

2009-03-01

Expected to finish

2012-06-01

Last updated by the study team

2021-05-24

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• men and women age 18-65
• current KM using the clinician-administered Structured Clinical Interview for Kleptomania (SCI-K)
• stealing behavior within 2 weeks prior to enrollment.

You may not qualify if…

• infrequent stealing (i.e. less than one time per week) that does not meet proposed criteria for kleptomania (KM)
• unstable medical illness or clinically significant abnormalities on laboratory tests or physical examination at screen
• history of seizures
• myocardial infarction within 6 months
• current pregnancy or lactation, or inadequate contraception in women of childbearing potential
• a need for medication other than memantine with possible psychotropic effects or unfavorable interactions
• clinically significant suicidality
• current Axis I disorder determined by the Structured Clinical Interview for the DSM (SCID) and SCID-compatible modules for impulse control disorders (Grant et al., 2005), except for nicotine dependence
• lifetime history of bipolar disorder type I or II, dementia, schizophrenia, or any psychotic disorder determined by SCID
• current or recent (past 3 months) DSM-IV substance abuse or dependence
• positive urine drug screen at screening
• initiation of psychotherapy or behavior therapy within 3 months prior to study baseline
• previous treatment with memantine; and 14) treatment with investigational medication or depot neuroleptics within 3 months, with fluoxetine within 6 weeks, or with other psychotropics within 2 weeks prior to study baseline.

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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