Pharmacotoxicology of Trichloroethylene Metabolites

Completed · Not applicable

Conditions studied: Congenital Lactic Acidosis

In brief

To establish the relationship between human MAAI haplotype and DCA and tyrosine metabolism. This aim test the postulates that MAAI haplotype determines, and thus can predict,1) dose-dependent DCA kinetics and biotransformation.

Key facts

Study ID

NCT00874276

Run by

University of Florida

People needed

21

Starts

2009-08-01

Expected to finish

2012-11-01

Last updated by the study team

2015-06-04

Who can join

Age: 21 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy volunteers

You may not qualify if…

• Pregnancy
• Other medications
• Psychiatric illness on meds
• Abnormal labs

Where it is running

• University of Florida Shands Hospital — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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