S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Completed · Phase 2
Conditions studied: Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vandetanib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. It is not yet known whether docetaxel is more effective when given alone or together with vandetanib. PURPOSE: This randomized phase II trial is studying docetaxel given together with or without vandetanib to see how well it works in treating patients with persistent or recurrent ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cancer.
Key facts
- Study ID
- NCT00872989
- Run by
- SWOG Cancer Research Network
- People needed
- 129
- Starts
- 2010-03-01
- Expected to finish
- 2014-05-01
- Last updated by the study team
- 2016-12-19
Who can join
Age: 18 and older, up to 120. Sex: female. Healthy volunteers: not accepted.
Where it is running
- Alaska Regional Hospital Cancer Center — Anchorage, Alaska, United States
- Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona, United States
- NEA Medical Center - Stadium Boulevard — Jonesboro, Arkansas, United States
- Alta Bates Summit Comprehensive Cancer Center — Berkeley, California, United States
- Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center — Burbank, California, United States
- Peninsula Medical Center — Burlingame, California, United States
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Contra Costa Regional Medical Center — Martinez, California, United States
- Tibotec Therapeutics - Division of Ortho Biotech Products, LP — Marysville, California, United States
- El Camino Hospital Cancer Center — Mountain View, California, United States
- Highland General Hospital — Oakland, California, United States
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center — Orange, California, United States
- University of California Davis Cancer Center — Sacramento, California, United States
- California Pacific Medical Center - California Campus — San Francisco, California, United States
- Doctors Medical Center - San Pablo Campus — San Pablo, California, United States
- Sutter Health - Western Division Cancer Research Group — San Rafael, California, United States
- Tahoe Forest Cancer Center — Truckee, California, United States
- Sutter Solano Medical Center — Vallejo, California, United States
- San Luis Valley Regional Medical Center — Alamosa, Colorado, United States
- University of Colorado Cancer Center at UC Health Sciences Center — Aurora, Colorado, United States
- Shaw Regional Cancer Center — Edwards, Colorado, United States
- Valley View Hospital Cancer Center — Glenwood Springs, Colorado, United States
- Providence Cancer Center at Providence Hospital — Mobile, Alabama, United States
Full record on ClinicalTrials.gov
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