Assessment of Pain in People With Thalassemia
Completed
Conditions studied: Thalassemia
In brief
Thalassemia is an inherited blood disorder that can result in mild to severe anemia. People with thalassemia often experience pain, but the exact sources and prevalence of pain remain unknown. This study will examine the prevalence and severity of pain in people with thalassemia who are treated with regular blood transfusions and people with thalassemia who are not treated with regular blood transfusions.
Key facts
- Study ID
- NCT00872339
- Run by
- Carelon Research
- People needed
- 252
- Starts
- 2009-03-01
- Expected to finish
- 2010-12-01
- Last updated by the study team
- 2014-06-05
Who can join
Age: 12 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Thalassemia, as documented by clinical diagnosis, including the following:
- B-thalassemia (intermedia or major)
- Hgb H disease
- Hgb H with non-deletional mutations (e.g., Hgb H Constant Spring)
- E-B-thalassemia
- Homozygous alpha thalassemia
- Other thalassemic conditions not explicitly excluded
- Thalassemia intermedia due to heterozygous B mutation with an alpha excess
- Participants can be of any race, ethnicity, and either gender.
You may not qualify if…
- Thalassemia trait (i.e., single recessive B gene mutation, 2 gene alpha mutation) and thalassemia Hgb S, C, or D compound heterozygotes
- Unwillingness or inability to complete the Brief Pain Inventory (BPI) on a quarterly basis
- Has had a successful bone marrow transplant
Where it is running
- Children's Hospital and Research Institute at Oakland — Oakland, California, United States
- Children's Healthcare of Atlanta — Atlanta, Georgia, United States
- Children's Memorial Hospital of Chicago — Chicago, Illinois, United States
- Children's Hospital of Boston — Boston, Massachusetts, United States
- Weill Medical College — New York, New York, United States
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
- Baylor College of Medicine — Houston, Texas, United States
- Toronto General Hospital — Toronto, Ontario, Canada
Full record on ClinicalTrials.gov
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