Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement
Completed · Phase 3
Conditions studied: Breast Adenocarcinoma, DS Stage I Plasma Cell Myeloma, DS Stage II Plasma Cell Myeloma, Metastatic Malignant Neoplasm to the Bone, Pain, Musculoskeletal Complication, Urinary Complications
In brief
This randomized phase III trial studies two different schedules of zoledronic acid to compare how well they work in reducing bone-related complications in patients with breast cancer, prostate cancer, or multiple myeloma that has spread to other places in the body and have bone involvement. Bone-related complications are a major cause of morbidity in patients with metastatic prostate cancer, breast cancer, and multiple myeloma. Zoledronic acid may stop the growth of cancer cells in the bone and may help relieve some of the symptoms caused by bone metastases. It is not yet known whether giving zoledronic acid more or less frequently is more effective in treating patients with metastatic cancer that has spread to the bone.
Key facts
- Study ID
- NCT00869206
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 1822
- Starts
- 2009-03-01
- Expected to finish
- 2017-01-01
- Last updated by the study team
- 2018-11-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
- East Bay Radiation Oncology Center — Castro Valley, California, United States
- Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California, United States
- North Bay Cancer Center — Fairfield, California, United States
- Valley Medical Oncology — Fremont, California, United States
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Contra Costa Regional Medical Center — Martinez, California, United States
- Memorial Medical Center — Modesto, California, United States
- Camino Medical Group - Treatment Center — Mountain View, California, United States
- El Camino Hospital Cancer Center — Mountain View, California, United States
- Leavey Cancer Center at Northridge Hospital Medical Center — Northridge, California, United States
- Highland General Hospital — Oakland, California, United States
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
- Bay Area Breast Surgeons, Incorporated — Oakland, California, United States
- CCOP - Bay Area Tumor Institute — Oakland, California, United States
- Larry G Strieff MD Medical Corporation — Oakland, California, United States
- Tom K Lee, Incorporated — Oakland, California, United States
- Palo Alto Medical Foundation — Palo Alto, California, United States
- Feather River Hospital Cancer Center — Paradise, California, United States
- Study site — Pismo Beach, California, United States
- Naval Medical Center - San Diego — San Diego, California, United States
- Veterans Affairs Medical Center - San Diego — San Diego, California, United States
- Doctors Medical Center - San Pablo Campus — San Pablo, California, United States
- Aurora Presbyterian Hospital — Aurora, Colorado, United States
- Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital — Fairbanks, Alaska, United States
Full record on ClinicalTrials.gov
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