Preventing Propofol-associated Injection Pain

Completed · Phase 4 · Has a placebo group

Conditions studied: Pain

In brief

Injection of propofol is associated with discomfort in subsets of patients. Local anesthetics have been shown to attenuate this response in some patients. This randomized, double-blind, placebo-controlled trial tests the hypothesis that lidocaine mixed with propofol will be superior to lidocaine administered directly into the vein, under tourniquet control, prior to injection of propofol. Both groups are expected to be superior to placebo.

Key facts

Study ID

NCT00864682

Run by

Benaroya Research Institute

People needed

156

Starts

2008-01-01

Expected to finish

2009-04-01

Last updated by the study team

2021-01-27

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• weight >40kg, <100kg
• ambulatory surgery

You may not qualify if…

• allergy to propofol or lidocaine
• taking opioids, benzodiazepines, or nonsteroidal antiinflammatory drugs (NSAIDs)

Where it is running

• Benaroya Research Institute — Seattle, Washington, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.