Chemotherapy or Observation in Treating Patients With Early Stage Non-Small Cell Lung Cancer
Stopped early · Phase 3
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as vinorelbine, cisplatin, docetaxel, gemcitabine, and pemetrexed disodium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Sometimes after surgery, the tumor may not need more treatment until it progresses. In this case, observation may be sufficient. It is not yet known whether chemotherapy is more effective than observation in treating patients who have undergone surgery for stage I non-small cell lung cancer. PURPOSE: This randomized phase III trial is studying four chemotherapy regimens to see how well they work compared with observation in treating patients with early stage non-small cell lung cancer.
Key facts
- Study ID
- NCT00863512
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 34
- Starts
- 2009-03-01
- Expected to finish
- 2012-11-01
- Last updated by the study team
- 2017-03-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UAB Comprehensive Cancer Center — Birmingham, Alabama, United States
- Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center — Burbank, California, United States
- Glendale Memorial Hospital Comprehensive Cancer Center — Glendale, California, United States
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Study site — Pismo Beach, California, United States
- Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center — Pomona, California, United States
- Helen and Harry Gray Cancer Center at Hartford Hospital — Hartford, Connecticut, United States
- Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital — Fort Lauderdale, Florida, United States
- Memorial Cancer Institute at Memorial Regional Hospital — Hollywood, Florida, United States
- Ella Milbank Foshay Cancer Center at Jupiter Medical Center — Jupiter, Florida, United States
- CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
- Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler — Savannah, Georgia, United States
- Resurrection Medical Center — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Elkhart Clinic, LLC — Elkhart, Indiana, United States
- Michiana Hematology-Oncology, PC - Elkhart — Elkhart, Indiana, United States
- Elkhart General Hospital — Elkhart, Indiana, United States
- Howard Community Hospital — Kokomo, Indiana, United States
- Center for Cancer Therapy at LaPorte Hospital and Health Services — La Porte, Indiana, United States
- Michiana Hematology-Oncology, PC - South Bend — Mishawaka, Indiana, United States
- Saint Joseph Regional Medical Center — Mishawaka, Indiana, United States
- Michiana Hematology Oncology PC - Plymouth — Plymouth, Indiana, United States
- CCOP - Northern Indiana CR Consortium — South Bend, Indiana, United States
- Memorial Hospital of South Bend — South Bend, Indiana, United States
- Regional Medical Center — Anniston, Alabama, United States
Full record on ClinicalTrials.gov
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