Hemodynamic Effects of Spironolactone in Patients With Heart Failure

Completed · Not applicable

Conditions studied: Congestive Heart Failure

In brief

To determine if the beneficial effect of spironolactone in patients with congestive heart failure is in part due to its intrinsic inotropic action. Randomized, two group placebo controlled, single blind study.

Key facts

Study ID

NCT00860340

Run by

University of Toledo Health Science Campus

People needed

18

Starts

2003-02-01

Expected to finish

2006-10-01

Last updated by the study team

2014-12-10

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• CHF
• 21 - 80 years
• Serum creatinine < 2 mg/dL
• Serum potassium 2.7 - 4.5 mg/dL measured within past 4 weeks

You may not qualify if…

• Less than 21 years
• Pregnancy

Where it is running

• Medical University of Ohio — Toledo, Ohio, United States

Full record on ClinicalTrials.gov

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