Myocardial Stress Perfusion Imaging With Dual Source CT
Completed · Not applicable
Conditions studied: Coronary Artery Disease
In brief
The investigators propose a novel technique using dual source multidetector computed tomography (DSCT) where information on both coronary anatomy and myocardial perfusion is obtained in a single scan. The investigators hypothesize that a coronary CTA protocol can be devised to obtain resting myocardial perfusion, myocardial perfusion after stress, and coronary anatomy. Hence, one diagnostic test will be able to detect the presence of coronary plaque as well as assess the functional significance of a stenosis.
Key facts
- Study ID
- NCT00853671
- Run by
- Massachusetts General Hospital
- People needed
- 50
- Starts
- 2008-04-01
- Expected to finish
- 2010-04-01
- Last updated by the study team
- 2018-12-17
Who can join
Age: 40 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- A prior adenosine or exercise stress SPECT exam with high likelihood of being referred to the cardiac catheterization laboratory for invasive angiogram
- Age > 40 years old
- Able to comprehend and sign the consent form.
You may not qualify if…
- Acute coronary syndromes (unstable angina, non-ST elevation myocardial infarction, ST elevation myocardial infarction)
- Unstable clinical conditions (i.e. hemodynamic instability, arrhythmias)
- Premenopausal women who have a positive pregnancy test.
- Serum Creatinine level ≥1.5 mg/dl as an indicator of renal insufficiency.
- Known allergy to iodinated contrast agents
- Atrial fibrillation
- Asthma
- Critical aortic stenosis
- Systolic blood pressure < 90 mmHg
- Advanced heart block
Where it is running
- Massachusetts General Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.