Sedation and Pain (The Effect of IV Sedation on Pain Perception)
Completed · Not applicable
Conditions studied: Pain
In brief
The investigators propose to evaluate the potential effect of sedation on pain perception in two ways, by asking for a participant's pain rating(subjective) and by evaluating a subject's brain activation using fMRI(objective).
Key facts
- Study ID
- NCT00853333
- Run by
- University of Alabama at Birmingham
- People needed
- 86
- Starts
- 2008-11-01
- Expected to finish
- 2012-01-01
- Last updated by the study team
- 2014-06-26
Who can join
Age: 19 and older, up to 40. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy subjects
- 19 years or older able to follow study instructions
You may not qualify if…
- Age less than 19 or greater than 40
- Pregnant female
- Obesity (BMI > or =35)
- Non-English speaking/reading participants
- Sleep apnea
- Pulmonary problems such as moderate or severe bronchial asthma
- Cardiovascular problems such as hypertension
- History of claustrophobia
- Presence of a pacemaker, defibrillator, surgically placed metallic object (e.g., hip replacement)or other implanted device
- Presence of an unremoved bullet or shrapnel in the body
- Presence of a prosthetic that is not removable
- Presence of a hearing aid needed for hearing
- Head girth exceeding that of the head coil used in the magnet
- Extensive metalwork on or in teeth, or irremovable false teeth or bridgework
- Epilepsy
- Chronic analgesic medication
- Excessive tattoos (due to local skin heating with tattoos containing ferromagnetic particles)
- History of surgery for which details are unavailable
- Allery due to study drugs
- History of drug abuse
Where it is running
- University of Alabama at Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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