Randomized Study Comparing Genz-644470, Placebo, and Sevelamer Carbonate in Chronic Kidney Disease Patients on Hemodialysis

Completed · Phase 2 · Has a placebo group

Conditions studied: Kidney Failure, Chronic

In brief

The purpose of this clinical study is to compare the effects of Genz-644470 with the effects of placebo and sevelamer carbonate (Renvela®) on the reduction of serum phosphorus in hyperphosphatemic chronic kidney disease participants on hemodialysis.

Key facts

Study ID

NCT00853242

Run by

Genzyme, a Sanofi Company

People needed

349

Starts

2009-02-01

Expected to finish

2009-08-01

Last updated by the study team

2015-05-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Serum phosphate level greater than (>) 5.5 milligram per deciliter (mg/dL) (1.78 millimole per liter [mmol/L]) after discontinuation of current phosphate binder therapy
• Men or women 18 years or older

You may not qualify if…

• Have active dysphagia or swallowing disorder or a predisposition to or current bowel obstruction, ileus, or severe gastrointestinal motility disorders including severe constipation

Where it is running

• Study site — Birmingham, Alabama, United States
• Study site — Hot Springs, Arkansas, United States
• Study site — Bakersfield, California, United States
• Study site — Los Angeles, California, United States
• Study site — Paramount, California, United States
• Study site — Pembroke Pines, California, United States
• Study site — Porterville, California, United States
• Study site — Riverside, California, United States
• Study site — San Dimas, California, United States
• Study site — Whittier, California, United States
• Study site — Denver, Colorado, United States
• Study site — Washington D.C., District of Columbia, United States
• Study site — Hudson, Florida, United States
• Study site — Ocala, Florida, United States
• Study site — Tampa, Florida, United States
• Study site — Augusta, Georgia, United States
• Study site — Marietta, Georgia, United States
• Study site — Gurnee, Illinois, United States
• Study site — Indianapolis, Indiana, United States
• Study site — Wichita, Kansas, United States
• Study site — Lexington, Kentucky, United States
• Study site — Bethesda, Maryland, United States
• Study site — Pontiac, Michigan, United States
• Study site — Southfield, Michigan, United States
• Study site — Alexander City, Alabama, United States

Full record on ClinicalTrials.gov

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