Lipoprotein Effects of Substituting Beef Protein for Carbohydrate

Completed · Not applicable

Conditions studied: Healthy, Cardiovascular Disease, Atherogenic Dyslipidemia

In brief

The purpose of this study is to test whether replacing dietary carbohydrate with protein, using beef as the primarily source of protein, will improve risk factors for cardiovascular disease.

Key facts

Study ID

NCT00852267

Run by

UCSF Benioff Children's Hospital Oakland

People needed

67

Starts

2008-01-01

Expected to finish

2009-12-01

Last updated by the study team

2020-12-24

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Blood pressure less than 150/90
• Body mass index (BMI)≥ 20 and ≤ 35 kg/m2
• Non-smoker
• Agrees not to consume alcohol during the study
• Agrees to abstain from taking dietary supplements during the study
• LDL-cholesterol and total cholesterol < 95th percentile for age and sex
• Fasting triglycerides < 500 mg/dL
• Fasting glucose concentration < 126 mg/dL
• Hematocrit (HCT) ≥ 36%
• At least three months of a weight-stable state (± 3% of body weight)

You may not qualify if…

• Personal history of coronary heart disease, cerebrovascular disease, peripheral vascular disease, diabetes, lung disease, bleeding disorder, liver or renal disease, HIV or of cancer (other than skin cancer) in the last five years
• Taking drugs known to affect lipid metabolism or insulin resistance, hormones, or the blood thinning agent warfarin
• Abnormal thyroid stimulating hormone (TSH)
• Strength trains with resistance weights more than four hours per week

Where it is running

• Cholesterol Research Center — Berkeley, California, United States

Full record on ClinicalTrials.gov

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