A Study of the Efficacy of Subcutaneous Phosphatidylcholine and Deoxycholate Injections for Localized Fat Removal

Stopped early · Not applicable · Has a placebo group

Conditions studied: Obesity

In brief

The primary objective of this study is to determine the efficacy of phosphatidylcholine and deoxycholate subcutaneous injections for localized fat removal. Subcutaneous injections of the study drug will be efficacious in decreasing localized fat deposits due to the known fat necrosis effects on fat tissue after study drug tissue incubation.

Key facts

Study ID

NCT00851747

Run by

The Cleveland Clinic

People needed

18

Starts

2009-02-01

Expected to finish

2009-10-01

Last updated by the study team

2018-04-17

Who can join

Age: 25 and older, up to 70. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age 25 and over
• BMI of 18.5-29.99
• Two localized areas of fat deposition on the upper and lower torso that have failed on self-reported diet and exercise
• The subject is in good health
• The subject has the willingness and the ability to understand and provide informed consent

You may not qualify if…

• Under 25 years of age
• Pregnancy or Lactation
• BMI≥ 30
• Subjects with known eating disorders or a history of weight loss/gain of 5 pounds or more within the past 6 months
• Subjects with hepatrophy, nephopathy, diabetes, hyperthyroidism, neoplasias, AIDS or other immuno-compromised illness, allergies to eggs or soy, poorly controlled hypertension, or autoimmune disease
• Subjects currently taking blood thinners or who have had chemotherapy or radiation within the last 6 months
• Subjects with an open, non-healing sore or infection near site of injection
• Subjects with active eczema or psoriasis
• Subjects who are unable to understand the protocol or to give informed consent
• Subjects with mental illness

Where it is running

• Cleveland Clinic Foundation — Cleveland, Ohio, United States
• Cleveland Clinic Foundation — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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