Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate Carcinoma
Stopped early · Not applicable
Conditions studied: Prostate Cancer
In brief
The purpose of the present study is to find out if MRI techniques examining (1) the motion of water molecules in the prostate (diffusion sensitive MRI), (2) the difference in blood flow to the prostate (dynamic contrast enhanced MRI), and (3) differences in chemical composition of the prostate (MR spectroscopy), can be used to detect prostate cancer early and non-invasively. Localization of the cancer within the prostate would be of particular importance in focal cryoablation of prostate carcinoma which we hope to improve as a result of this project. Additional aim of the study is to correlate expression of genes believed to pay a role in prostate cancer with MRI findings.
Key facts
- Study ID
- NCT00851682
- Run by
- Washington University School of Medicine
- People needed
- 65
- Starts
- 2009-01-01
- Expected to finish
- 2014-02-01
- Last updated by the study team
- 2018-10-31
Who can join
Age: 20 and older, up to 85. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- patients who have been diagnosed with prostate cancer and are scheduled for radical prostatectomy or for brachytherapy
- patients who have not received any preoperative treatment for their diagnosis of prostate cancer
You may not qualify if…
- patients with implants that are electronically, magnetically, or mechanically active
- patients with intracranial aneurysm clips
- patients who have undergone cosmetic eyelid surgery
- patients with history of pheochromocytoma, insulinoma and acute glaucoma
- patients with estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m2
Where it is running
- Washington University School of Medicine — St Louis, Missouri, United States
- Washington University School of Medicine — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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