Cognitive Remediation in Posttraumatic Stress Disorder (PTSD)

Completed · Not applicable

Conditions studied: Posttraumatic Stress Disorder

In brief

The purpose of this study is to gather feasibility data on cognitive remediation therapy (CRT) as an alternative intervention for PTSD. CRT is a standardized intervention that involves performing cognitive exercises to improve attention, processing speed, and memory through practice. Although the primary objective will be to determine the effect of CRT on cognitive functioning in PTSD, data on PTSD symptom severity and other clinical measures will also be examined to assess whether and to what degree cognitive alterations and symptom severity might be linked. CogPack, a computer-based form of CRT, would be employed for this project. Participants will be randomized to receive CRT or to play the video game Tetris as a control condition.

Key facts

Study ID

NCT00850447

Run by

Bronx VA Medical Center

People needed

2

Starts

2008-10-01

Expected to finish

2011-03-01

Last updated by the study team

2012-02-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female combat veterans with a current diagnosis of PTSD with a minimum duration of six months
• Age 18 years and older
• Capable of understanding, reading, and writing in English

You may not qualify if…

• Incapable and/or unwilling to provide written informed consent prior to participation
• Less than 11 years of formal education
• The veteran, the veteran's physician, or the study physician thinks that the veteran's clinical state necessitates hospitalization
• Response of 3 or 4 on the suicidality items of the Hamilton Depression Rating Scale or an assessed serious suicide risk
• Current substance and/or alcohol abuse and/or dependence, or abuse/dependence within the previous 6 months which contraindicates participation in the judgment of the evaluating clinician
• A lifetime history of schizophrenia, schizoaffective disorder, bipolar disorder, organic mental disorder, or dementia

Where it is running

• James J. Peters Veterans Affairs Medical Center — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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