Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate

Stopped early · Not applicable

Conditions studied: Hypertension

In brief

The purpose of the study is to compare the effects of nebivolol and metoprolol on 24-hour ambulatory blood pressure characteristics and basal metabolic rates in patients with hypertension.

Key facts

Study ID

NCT00849810

Run by

University of Mississippi Medical Center

People needed

1

Starts

2009-01-01

Expected to finish

2010-11-01

Last updated by the study team

2013-03-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years old or older
• currently be treated at a University of MS Medical Center Internal Medicine Clinics
• currently taking metoprolol succinate for hypertension
• have their hypertension controlled (<140/90).

You may not qualify if…

• uncontrolled hypertension
• severe renal or moderate hepatic impairment
• currently taking CYP 2D6 inducers/inhibitors
• recent stroke (less than 6 months)
• recent myocardial infarction (less than 6 months)
• congestive heart failure
• diagnosed obstructive sleep apnea
• atrial fibrillation
• arm circumference >50 cm

Where it is running

• University of Mississippi Medical Center — Jackson, Mississippi, United States

Full record on ClinicalTrials.gov

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