Measures to Lower the Stress Response in Pediatric Cardiac Surgery

Completed · Phase 2

Conditions studied: Tetralogy of Fallot (TOF), Ventricular Septal Defects (VSD), Atrioventricular Septal Defects (AVSD)

In brief

Cardiac surgery induces a measurable stress response in patients which leads to increased morbidity and mortality post-operatively. Through clinical observation, anesthesiologists have determined that varying the combinations of anesthesia drugs used during surgery and just after reduces the stress response, and by extension, morbidity and mortality. However, only a few studies have explored this phenomenon scientifically.

Key facts

Study ID

NCT00848393

Run by

Nationwide Children's Hospital

People needed

52

Starts

2008-11-01

Expected to finish

2013-12-01

Last updated by the study team

2018-07-27

Who can join

Age: 0 and older, up to 3. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Childrens with the diagnosis of tetralogy of fallot, ventricular septal defect and atrioventricular septal defect who are under one year of age.

You may not qualify if…

• Patients who are having reoperation.
• Patients with comorbidities, such as heart failure.
• Patients receiving digoxin preoperatively.

Where it is running

• Nationwide Children's Hospital — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.