Chronic Post Breast Surgery Pain
Stopped early · Not applicable · Has a placebo group
Conditions studied: Breast Cancer
In brief
The purpose of this study is to learn if paravertebral block (PVB) will reduce chronic pain after surgery. Our hypothesis is that chronic pain from breast surgery as a consequence of central sensitization can be prevented by blocking sensory input to the CNS during surgery and the immediate post-operative period.
Key facts
- Study ID
- NCT00847067
- Run by
- Mayo Clinic
- People needed
- 40
- Starts
- 2009-02-01
- Expected to finish
- 2010-04-01
- Last updated by the study team
- 2010-06-11
Who can join
Age: 18 and older, up to 80. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Female patient who are ≥ 18 and ≤ 80 years of age.
- Patient with diagnosis of breast cancer.
- Patient scheduled for modified radical mastectomy or lumpectomy with axillary node dissection
- Patient scheduled for one of the above listed surgeries with or without sentinel, partial, or complete axillary lymph node dissection
- Patients scheduled for one of the aforementioned surgeries with or without immediate or delayed reconstruction.
You may not qualify if…
- Pre-existing peripheral neuropathy
- Pre-existing chronic pain
- Bilateral procedure
- Previous breast surgery, except biopsy
- Inability to read, write or speak English.
- Allergy to amide local anesthetics
- Contraindications to paravertebral nerve block including, but not limited to severe scoliosis of the spine, skin lesion overlying the block area, abnormal coagulation studies (some of these may not be known until after informed consent is obtained)
- Pregnancy
- Emergency surgery
- Previous recipients of peripheral nerve block.
- Medical professional whose experience includes caring for patients who have had peripheral nerve blocks.
Where it is running
- Mayo Clinic Florida — Jacksonville, Florida, United States
Full record on ClinicalTrials.gov
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