Interactions Between Physical Activity and Cannabis Use in Adults

Completed · Not applicable

Conditions studied: Cannabis Dependence

In brief

In this study the investigators will explore the relationship between physical activity and cannabis use. The investigators will compare regional brain activation detected by imaging technique(fRMI) before and after exercise in cannabis users and compare results with results from controls. The investigators hypothesize that the regional brain activation in response to visual cues (pictures related to cannabis use and food) will be different in cannabis users than in controls and that exercise will significantly alter brain responses to the cues.

Key facts

Study ID

NCT00838448

Run by

Vanderbilt University

People needed

30

Starts

2009-01-01

Expected to finish

2013-06-01

Last updated by the study team

2013-06-12

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Cases and Controls must:
• Be able to understand the study and provide written informed consent.
• Be male or female 18 -35 years of age.
• Be in generally good health
• If female of childbearing potential, have a negative serum pregnancy test on study day
• Cases must:
• Meet criteria for cannabis dependence as primary diagnosis as determined by the Substance Abuse module of SCID (Structured Clinical Interview for DSM-IV).
• Not currently seeking treatment for cannabis dependence.
• Have a positive urine drug test for cannabis on the study day
• Avoid alcohol and other recreational drug use (except cannabis and/or nicotine) for 48 h before testing.

You may not qualify if…

• Cases and Controls must not:
• Be pregnant or lactating
• Have implanted electrical medical device (e.g. pacemaker, vagal nerve stimulator)
• Have non-secure metallic foreign bodies
• Have met criteria for another axis 1 diagnosis in the past 6 months
• Receive psychotropically active or vasoactive medications (within 6 weeks of screen day)
• Have chronic medical illness
• Have epilepsy
• Have a history of head injury that required hospitalization
• Have claustrophobia
• Have orthopedic or other problems precluding them from performing exercise protocol
• Have body mass index (BMI) less than 19 kg/m2
• Weighing more than 275 pounds (MRI table limit)
• Cases must not:
• Have current dependence, as determined by the SCID, on any psychoactive substance other than nicotine and/or cannabinoid
• Have any serious medical or psychiatric illnesses and/or clinically significant symptoms, which in the judgment of the PI or his/her designee would make them unsafe, or would make compliance with the study protocol difficult or put the study staff at undue risk

Where it is running

• Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.