Enoxaparin and/or Minocycline in Acute Stroke
Stopped early · Not applicable
Conditions studied: Acute Ischemic Stroke
In brief
The purpose of this study is to investigate whether enoxaparin, minocycline, or both medications in combination may help in recovery from acute stroke. Enoxaparin (brand name Lovenox®) is a medication approved for use in humans to prevent and to treat blood clots in deep veins in certain specific medical situations. Minocycline (brand name Minocin®) is a tetracycline antibiotic approved to treat a number of bacterial infections in humans. The investigators are studying these medications in acute human stroke because they have each been separately shown to reduce the amount of injured brain tissue in rats made to have acute ischemic stroke experimentally. In a human trial comparing minocycline with placebo (a sugar pill) acute ischemic stroke patients who took minocycline had better recovery after 1 week, 1 month and 3 months than patients who took placebo.
Key facts
- Study ID
- NCT00836355
- Run by
- NYU Langone Health
- People needed
- 6
- Starts
- 2009-04-01
- Expected to finish
- 2010-01-01
- Last updated by the study team
- 2016-04-29
Who can join
Age: 18 and older, up to 95. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Bellevue Hospital Center — New York, New York, United States
- New York University Langone Medical Center — New York, New York, United States
- Bellevue Hospital Center — New York, New York, United States
- New York University Langone Medical Center — New York, New York, United States
Full record on ClinicalTrials.gov
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