Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer

Completed

Conditions studied: Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma

In brief

The purpose of this study is to determine the difference of skin carotenoid levels between subjects with previous squamous cell carcinomas (SCC), subjects with previous basal cell carcinomas (BCC) and a control group.

Key facts

Study ID

NCT00836342

Run by

Massachusetts General Hospital

People needed

81

Starts

2009-02-01

Expected to finish

2012-01-01

Last updated by the study team

2012-07-25

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects between 50 and 75 years old without history of previous SCC or BCC.
• Fitzpatrick skin types I-IV.
• Willing and able to understand and sign informed consent.
• Able to complete study and comply with study procedures

You may not qualify if…

• Regular ingestion of supplements containing carotenoids or vitamin A in the past 4 weeks.
• Use of topical retinoids in the past 4 weeks.
• Treatment with systemic retinoids in the past 6 months.
• Dermatologic conditions that require the use of interfering topical or systemic therapy or that might interfere with study assessments such as, but not limited to, palmar psoriasis, hand dermatitis or palmo-plantar keratoderma.
• Previous history of psoriasis.
• Clinically significant abnormal findings or conditions, which might, in the opinion of the Principal Investigator, interfere with study evaluations or pose a risk to subject safety during the study.
• Subjects who are known to be pregnant or planning a pregnancy.

Where it is running

• Clinical Unit for Research Trials in Skin - MGH — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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