Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties

Completed · Not applicable

Conditions studied: Knee Osteoarthritis, Hip Osteoarthritis

In brief

Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time. The purpose of this study is to evaluate the use of Quill as part of our layered closure compared to using our traditional sutures. The study timeline begins at the time of the surgical procedure and continues through the routine follow-up of total joint replacements at 2, 6, and 12 weeks, and will conclude at the six month post-operative office visit. Primary Objectives: * To evaluate the safety and efficacy of wound closure in primary hip and knee replacements using a bidirectional barbed suture (knotless) compared to a traditional layered (vicryl) wound closure. Secondary Objectives: * Establish the all around (intra-operative and post-operative) cost-savings potential in using a knotless wound closure compared to that of a layered vicryl closure (our standard suture protocol). * Assess the overall cosmesis of the wound/scar as well as perceived presence of subcutaneous surgical knots, when using the knotless wound closure versus our traditional layered suture closure.

Key facts

Study ID

NCT00834483

Run by

Rush University Medical Center

People needed

65

Starts

2009-02-01

Expected to finish

2012-12-01

Last updated by the study team

2014-09-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients must be male or female of any race
• Ages 18-80 years old
• Patients must be undergoing a primary hip or knee arthroplasty
• Patients must be able to understand and willing to cooperate with study procedures
• Able to provide written and verbal informed consent

You may not qualify if…

• Allergy or intolerance to the study materials
• Surgical intervention during the past month for the treatment of the painful joint or its underlying etiology
• History of previous surgeries on the affected joint other than arthroscopy (open surgeries)
• History of any substance abuse or dependence within the last 6 months

Where it is running

• Rush university Medical Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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