Effect of Ketamine on Opioid-Induced Hyperalgesia

Completed · Not applicable · Has a placebo group

Conditions studied: Pain, Chronic Pain, Hyperalgesia

In brief

The purpose of this study is to compare pain threshold, pain tolerance, and wind up, as measured by QST, before and after a single dose of ketamine infusion under two clinical conditions: chronic pain patients on opioid therapy and chronic pain patients without opioid therapy.

Key facts

Study ID

NCT00833755

Run by

Massachusetts General Hospital

People needed

79

Starts

2008-09-01

Expected to finish

2016-04-01

Last updated by the study team

2020-07-23

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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