Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
Stopped early · Not applicable
Conditions studied: Patent Ductus Arteriosus, Prematurity
In brief
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a higher PDA closure rate than later use of Ibu. Early use is defined as medication given before the infant reaches 96 hrs old. Late use is defined as medication given when infant is more than 96 hrs old.
Key facts
- Study ID
- NCT00833365
- Run by
- University of Utah
- People needed
- 15
- Starts
- 2009-01-01
- Expected to finish
- 2011-11-01
- Last updated by the study team
- 2016-07-04
Who can join
Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Birth weight less than 1200gm
- Less than 28 weeks gestational age
- Confirmed Patent Ductus Arteriosus (PDA) via echocardiogram and clinical exam
You may not qualify if…
- Active Bleeding
- Currently being treated for Persistent Pulmonary Hypertension (PPHN)
- Cardiac anomalies
- Chromosomal abnormalities
- Endocrine, metabolic, renal, or hepatic disorders
Where it is running
- University of Utah — Salt Lake City, Utah, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.