Antibiotic Resistant Patterns of Conjunctival and Nasophayngeal Flora After Repeated Exposure to Topical Antibiotics

Completed

Conditions studied: Age-related Macular Degeneration

In brief

Repeated exposure to topical antibiotics may alter the normal bacteria on the eye and in the nose and increase rates of resistance. This study will determine whether repeated short-term exposure to topical antibiotic drops which are commonly prescribed after eye injections to reduce the chance of infection increase rates of resistant bacteria which are normally found on the eye and in the nose. We hypothesis that certain commercially available antibiotics may increase rates of bacteria resistance more so than others.

Key facts

Study ID

NCT00831961

Run by

Vanderbilt University

People needed

24

Starts

2009-01-01

Last updated by the study team

2015-12-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age greater than 18 with choroidal neovascularization with planned treatment with intravitreal injections

You may not qualify if…

• Use of topical antibiotics for any reason within 3 months, current use of systemic or topical antibiotics, known allergies to gatifloxacin, moxifloxacin, ofloxacin, and azithromycin

Where it is running

• Vanderbilt Eye Institute — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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