Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil

Completed · Phase 3 · Has a placebo group

Conditions studied: Alzheimer's Disease

In brief

The purpose of this study is to determine if Dimebon is safe and effective in patients with mild to moderate Alzheimer's disease on Donepezil.

Key facts

Study ID

NCT00829374

Run by

Medivation, Inc.

People needed

1003

Starts

2009-03-01

Expected to finish

2011-12-01

Last updated by the study team

2016-09-27

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Mild-to-moderate Alzheimer's disease (AD)
• Probable AD (Diagnostic Statistical Manual of Mental Disorders-IV-Text Revision (DSM-IV-TR))
• Mini-Mental State Examination (MMSE) score between 12 and 24, inclusive
• Stable on donepezil for at least 6 months

You may not qualify if…

• Other causes of dementia
• Major structural brain disease
• Unstable medical condition or significant hepatic or renal disease

Where it is running

• Study site — Sun City, Arizona, United States
• Study site — Tucson, Arizona, United States
• Study site — Costa Mesa, California, United States
• Study site — Encino, California, United States
• Study site — Escondido, California, United States
• Study site — Fresno, California, United States
• Study site — Garden Grove, California, United States
• Study site — La Jolla, California, United States
• Study site — Los Alamitos, California, United States
• Study site — Los Angeles, California, United States
• Study site — Martinez, California, United States
• Study site — Newport, California, United States
• Study site — Paramount, California, United States
• Study site — Pasadena, California, United States
• Study site — San Diego, California, United States
• Study site — San Francisco, California, United States
• Study site — Boulder, Colorado, United States
• Study site — Denver, Colorado, United States
• Study site — New Haven, Connecticut, United States
• Study site — Washington D.C., District of Columbia, United States
• Study site — Deerfield Beach, Florida, United States
• Study site — Delray Beach, Florida, United States
• Study site — Jacksonville, Florida, United States
• Study site — Miami, Florida, United States
• Study site — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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