Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries

Completed · Phase 2/Phase 3

Conditions studied: Hypertension, Diabetes

In brief

The study is being done to see if a drug shown to lower the risk of heart failure is also effective in reducing the stiffness of the arteries.

Key facts

Study ID

NCT00829296

Run by

University of Chicago

People needed

70

Starts

2009-01-01

Expected to finish

2013-04-01

Last updated by the study team

2016-02-05

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Established Type 2 diabetic not treated with insulin
• Stage 1 hypertensives blood pressure > 130/80 mmHg and < 160/100 mmHg
• BMI < 35
• Hemoglobin A1C < 8.5
• Must be postmenopausal or taking some form of birth control of surgically sterile

You may not qualify if…

• Acute myocardial infarction, unstable angina, stroke or TIA within the past year.
• Active angina in the last three months
• Diabetes requiring treatment with insulin
• Severe asthma
• Female who are pregnant, planning to be pregnant during the study period, lactating or women of childbearing potential who are not using a medically approved method of contraception
• Recent history of substance or alcohol abuse .
• Uncontrolled hypertension systolic blood pressure >160mmHg or diastolic blood pressure > 100 mmHg

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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