Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome
Completed · Phase 4 · Has a placebo group
Conditions studied: Acute Coronary Syndrome, Sleep Disorder
In brief
The purpose of the study is to examine the effects of Eszopiclone, a sleep aid, on inflammatory mediators and coagulability in patients with a recent myocardial infarction.
Key facts
- Study ID
- NCT00822679
- Run by
- University of Arizona
- People needed
- 5
- Starts
- 2007-10-01
- Expected to finish
- 2010-01-01
- Last updated by the study team
- 2016-12-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with recent (less than or equal to 8 weeks) "uncomplicated" acute myocardial infarction, can either be ST elevation MI (STEMI) or non-ST elevation MI (non-STEMI) and subsequent to successful treatment (percutaneous revascularization or medical therapy).
You may not qualify if…
- Obstructive sleep apnea (OSA, defined as apnea-hypopnea index > 15 per hour) or previous diagnosis of OSA.
- Patients with life-threatening arrhythmias (such as atrial fibrillation/flutter with hypotension, ventricular tachycardia, or ventricular fibrillation, or significant heart block that requires pacing [Type III, Type IIb]), cardiogenic shock, severe heart failure requiring high levels of inspired oxygen (FiO2 >40%), persistent chest pain despite medical or other interventions, and patients who are considered too unstable to participate for other medical reasons or complications (such as concomitant strokes, retroperitoneal hematoma, gastro-intestinal bleeding). Also excluded are patients with history of cardiac arrest during the same hospitalization.
- Unable to take oral medications
- Use of other sedative-hypnotics
- Hypersensitivity to Eszopiclone or any component of the formulation
- Pregnancy
Where it is running
- Southern Arizona VA Health Care System — Tucson, Arizona, United States
Full record on ClinicalTrials.gov
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