Behavioral Modification and Vesicare Versus Vesicare Alone for Urge Incontinence in Patients With Overactive Bladder

Stopped early · Phase 3

Conditions studied: Overactive Bladder

In brief

This study will help determine if behavior modification performed in conjunction with oral Vesicare anticholinergic therapy is more effective for treating overactive bladder symptoms than oral Vesicare anticholinergic therapy alone.

Key facts

Study ID

NCT00821184

Run by

Lahey Clinic

People needed

12

Starts

2006-09-01

Expected to finish

2008-09-01

Last updated by the study team

2018-04-04

Who can join

Age: 18 and older, up to 80. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female patients > 18 years of age
• OAB symptoms for > 3 months
• Symptoms defined as greater than 3 episodes/week of an uncontrolled urge to void causing incontinence.
• May or may not be accompanied by urinary frequency
• May be accompanied by stress urinary incontinence where stress incontinence does not predominate

You may not qualify if…

• Male Patients
• Underlying cortical or spinal cord pathology including SCI, MS, or
• Parkinson's Disease
• Urinary retention with post-void residual > 150cc
• Current treatment or treatment within the last 3 months with anticholinergic medications
• Patients not able to complete the questionaires or voiding diaries in English
• Pregnancy
• Active urinary tract infections
• Bladder Cancer or unevaluated hematuria
• Known diagnosis of narrow angle glaucoma
• Severe constipation
• History of reduced renal function (CrCl<30ml/min)
• History of liver disease
• Current treatment with cytochrome P450 inhibitor medications

Where it is running

• Lahey Clinic — Burlington, Massachusetts, United States

Full record on ClinicalTrials.gov

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