Impact of a Sleep Debt in Middle-Aged and Older Adults

Completed · Not applicable

Conditions studied: Sleep Restriction

In brief

This project has 6 aims. 1. To examine the impact of recurrent partial sleep loss in young, middle-aged and older men and women. Sleep will be restricted to 4 hours. 2. To test the hypothesis that extending bedtimes to allow for sleep recovery will reverse the metabolic, endocrine, and cardiovascular and neuro-behavioral alterations resulting from sleep restriction. Sleep will be extended to 12 hours following the 4 hour sleep restriction. 3. To test the hypothesis that there are age and gender differences in the total amount of sleep recovery obtained during the week of 12-hour bedtimes. 4. To test the hypothesis that there are age and gender differences in sleep capacity (the amount of time an individual can sleep per night when there is no sleep debt). 5. To test the hypothesis that sleep capacity is partly determined by baseline levels of slow-wave sleep and slow-wave activity. 6. To determine whether sleep capacity is related to sleep need by examining metabolic, endocrine, cardiovascular and neuro-behavioral changes with the amount of the individual sleep debt.

Key facts

Study ID

NCT00817700

Run by

University of Chicago

People needed

72

Starts

2005-04-01

Expected to finish

2008-05-01

Last updated by the study team

2017-01-11

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• normal weight
• healthy
• age 18-75 old

You may not qualify if…

• sleep disorder
• irregular life habits (shift workers, travelers)
• smokers
• on medication
• consumption of > 2 alcohol or caffeinated beverages/day

Where it is running

• The University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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