Fludeoxyglucose F 18 PET/CT Imaging in Finding Cancer in Patients Undergoing Surgery for Solid Tumors

Completed · Early Phase 1

Conditions studied: Unspecified Adult Solid Tumor, Protocol Specific

In brief

The purpose of this pilot study is to evaluate a combined and integrated technological approach of 18F-FDG-directed perioperative PET/CT imaging and intraoperative handheld gamma probe detection of known and occult disease in patients undergoing surgery for solid malignancies.

Key facts

Study ID

NCT00816335

Run by

Ohio State University Comprehensive Cancer Center

People needed

65

Starts

2008-10-01

Expected to finish

2011-08-01

Last updated by the study team

2016-04-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must be 18 years of age or older.
• Patients must either have a histologic-confirmed solid malignancy or have a suspected solid malignancy which has required a diagnostic preoperative PET/CT scan or for which a diagnostic preoperative PET/CT scan has been recommended
• Patients must clinically have been determined to be a candidate for the indicated surgical procedure.
• Patients may have had prior surgery and/or chemotherapy with no limit to the number of prior therapeutic procedures or chemotherapeutic regimens.
• Patients must have a performance status of 0, 1 or 2 by ECOG standards.
• Patients must give written informed consent, including consent to have IV line placed for 18F-FDG administration.
• Females of childbearing age must have a negative pregnancy test (by Beta HCG qualitative analysis), must have had a history of a surgical sterilization, or must give history of no menses in past twelve months.
• Fasting blood sugar less than 200 mg/dl.

You may not qualify if…

• Any patient with active CNS tumor involvement.
• Any patient who is pregnant or lactating.
• Any patient with a body size and habitus that is determined to prohibit use of the diagnostic equipment.
• Any patient with a tumor burden that is determined to be so great (as determined by preoperative PET/CT scanning or intraoperative findings) that further surgery is not advised.

Where it is running

• Ohio State University Medical Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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