Dose, Effects and Characteristics of Pilocarpine

Completed · Phase 4

Conditions studied: Open-angle Glaucoma

In brief

The purpose of this investigation, in which pilocarpine was given in repeated doses, was to evaluate: Part I - the effects of different concentrations of pilocarpine hydrochloride on intraocular pressure. Part II -the effects on intraocular pressure of glaucomatous patients to pilocarpine 2% when given once, twice and four daily. In addition, we studied various attributes of the eye which may serve as indicators of responsiveness of individual patients to pilocarpine.

Key facts

Study ID

NCT00803803

Run by

Wills Eye

People needed

37

Starts

1978-08-01

Expected to finish

1979-12-01

Last updated by the study team

2016-11-22

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Primary open-angle glaucoma
• Primary open-angle glaucoma suspect

Where it is running

• Wills Eye Glaucoma Service — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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