PET Imaging and Bariatric Surgery

Completed · Phase 1

Conditions studied: Obesity, Morbid

In brief

The purpose of this study is to look at certain areas of the brain that are related to addictive behaviors, such as overeating. These areas are called 'dopamine type 2 receptors' (DRD2/3) and other studies have shown that obese people have less of these. We propose that low DRD2/3 availability seen in morbidly obese subjects will change with weight loss associated with bariatric surgery.

Key facts

Study ID

NCT00801827

Run by

Vanderbilt University Medical Center

People needed

7

Starts

2007-01-01

Expected to finish

2012-06-01

Last updated by the study team

2017-03-17

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 18-60 years
• BMI equal to or greater than 40, or equal to or greater than 35 if there are 2 or more co-morbidities
• Weight less than 350 pounds

You may not qualify if…

• History of substance abuse,including but not limited to alcohol, cocaine, marijuana, heroin, nicotine
• History of psychiatric disorders
• Use of any antidepressants or psychotropics in the past 12 months
• Diabetes Mellitis
• Positive pregnancy test
• Any condition felt by the PI or co-investigators to interfere with the individual's ability to complete the study
• Subjects on medications for the last 3 months, such as sibutramine, which could affect the quality of the study, as determined by the PI
• Inability to travel to Nashville, TN four times

Where it is running

• Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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