Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation

Withdrawn before enrolling · Not applicable

Conditions studied: Bipolar Disorder, Schizophrenia, Healthy Controls

In brief

This study aims to gather additional information to support the theory that bipolar disorder is due to cellular (mitochondrial) dysfunction. To test this theory adults with bipolar disorder who are not currently symptomatic will receive a one-time brain scan (magnetic resonance spectroscopy \[MRS\] scan) with light stimulation. To test whether any MRS findings are specific to bipolar disorder, healthy controls and adults with schizophrenia will also be included in this study.

Key facts

Study ID

NCT00801567

Run by

Mclean Hospital

People needed

0

Starts

2010-06-01

Expected to finish

2010-06-01

Last updated by the study team

2012-03-12

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male of female
• 18-55 years
• Bipolar, currently euthymic OR schizophrenia, stable, OR healthy control with no history of psychiatric illness
• On stable medication with no changes in the two weeks prior to enrollment

You may not qualify if…

• History of substance abuse or dependence within 3 months of enrollment
• Positive urine drug screen
• Significant medical or neurological illness
• Pregnancy
• Any contraindication to magnetic resonance scanning, including claustrophobia

Where it is running

• McLean Hospital — Belmont, Massachusetts, United States
• McLean Hospital — Belmont, Massachusetts, United States

Full record on ClinicalTrials.gov

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